It is likely that the weight reduction observed in our study was greater than that found in previous clinical studies of GLP-1 RA because such studies ended before semaglutide and/or tirzepatide were available
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"We have people [calling the helpline] talking about celebrity culture, seeing media portraying rapid weight loss and just the negative impact that has as far as their own shame, guilt and body dissatisfaction." Universal screening to combat weight stigma There is little research on the effects of GLP-1 agonists in people with eating disorders, and Dr Trobe and Dr Cox agreed more research was needed
Because of their effectiveness and safety profile, GLP-1 treatments have become a popular option for individuals seeking medically guided weight management
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The Phase 2 trial documented these side effects across all dose groups, and the data tells a clear story: most symptoms are gastrointestinal, most are mild to moderate, and most improve as the body adapts